To learn the retrosynthesis and different classes of natural products for future endeavours in organic chemistry.
Classification, nomenclature, occurrence, general methods of structure determination, isoprene rule; structure determination, stereochemistry and synthesis of the following representative molecules: Citral, Geraniol, Menthol and β-Carotene.
Definition, nomenclature, physiological action, occurrence, general methods of structure elucidation, degradation, classification based on nitrogen heterocyclic ring. Structure, stereochemistry and synthesis of the following: Ephedrine, (+)-Nicotine and Morphine.
Occurrence, nomenclature, basic skeleton, Diel’s hydrocarbon and stereochemistry. Structure determination and synthesis of Cholesterol, Androsterone, Testosterone, Estrone.
Introduction to drugs, discovery, development and delivery. Agonists and antagonists.
Relation of Drug structure and its chemical and biological properties. Structure-activity and quantitative relationship. Drug targets.
General introduction and mode of action of- Anti-viral, antibiotics and anti-AIDS drugs.
Anti-inflammatory, analgesics, anti-histamines, anti-hypertensive and anti-cancer drugs.
General study of hormones, classification based on solubility and structures, mode of action of water soluble and fat soluble messengers.
Links:
[1] https://chemistry.iisuniv.ac.in/courses/subjects/natural-products-and-medicinal-chemistry
[2] https://chemistry.iisuniv.ac.in/academic-year/2018-2019