Biology for Chemists

Paper Code: 
CHY - 125(B)
Credits: 
2
Contact Hours: 
30.00
Max. Marks: 
100.00
Objective: 
Objectives: To learn the basic processes which link the biological systems with the chemical systems.
 
7.00
Unit I: 
The Matrix of Life
Origin of Life: elementary idea of prokaryotic and eukaryotic cell, difference between plant and animal cell, cell organelles and their functions: plasma membrane, chloroplast, mitochondria, golgi bodies, endoplasmic reticulum, lysosomes, ribosomes, nucleus.
Chemical bonds: Hydrogen bonds, covalent, ionic, Van-der waal interactions.
 
6.00
Unit II: 
Proteins
Amino acids: Essential and non essential, structure of zwitterions, Synthesis of amino acids by reductive amination , GS-GOGAT system and transamination,
Structure of proteins: primary, secondary-α helix and β pleated sheets, tertiary and Quaternary structure.
7.00
Unit III: 
Carbohydrates
Classification, structure and functions of monosaccharides, disaccharides, polysaccharides - starch, cellulose, glycogen, chitin and pectins.
Glycoconjugates: proteoglycans, glycoproteins and glycolipids              
 
5.00
Unit IV: 
Lipids
Structure and functions of lipids, Saturated and Unsaturated fatty acids, Classification- simple, compound and derived lipids (steroids and cholesterol), Synthesis of long chain fatty acids, α-oxidation, β-oxidation.
 
5.00
Unit V: 
Nucleic Acids
DNA- Double helical structure of DNA, types of DNA -A, B, C and Z forms, replication,                                                                                                               
RNA- RNA structure and its types- r RNA, mRNA, and tRNA, ribozymes
 
References: 
  1. Principles of Biochemistry;  Third Edition; A.L. Lehninger;  McMillan Press Limited, London, 2002.
  2. Biochemistry; Fifth Edition; L. Stryer; W.H. Freeman and Company, 2002.
  3. Biochemistry; First Indian Reprint;J. David Rawn, Tanima Publishing Corporation, New Delhi, 2004.
  4. Biochemistry; Second Edition; Voet and Voet;  John Wiley and Sons Inc., New york, 1995.
  5. Outline of Biochemistry; Fourth Edition; E.E. Conn and P.K. Stumpf; John Wiley and Sons Inc., New Delhi, 1994.
 
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