This course will enable the students to
gain advanced knowledge in synthetic organic and green chemistry so that the learner can suggest alternative reagents and reactions for performing desired organic transformations.
Course |
Learning outcome (at course level) |
Learning and Teaching Strategies |
Assessment Strategies |
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Course Code |
Course Title |
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24CHY426B |
Synthetic Strategies in Organic Chemistry (Theory) |
CO185: Plan an organic synthesis using suitable reagents to understand a range of more sophisticated approaches to synthesis (building on the knowledge from previous years). CO186: Apply reduction methods involving main group and transition metal reagents for the synthesis of complex organic compounds. CO187: Predict the newer synthetic tools for the selection of one type of reagent and reaction conditions over another in terms of efficacy in relation to a particular synthetic problem. CO188: Solve the mechanistic problems in a facile manner using the prescribed organocatalysts. CO189:Analyze the environmental impacts of chemistry and apply the green chemical tools, for cleaner environment and energy. CO190:Contribute effectively in course-specific interaction. |
Approach in teaching: Interactive lectures, tutorials, group discussions and e-learning.
Learning activities for the students: Peer learning, e- learning, problem solving through tutorials and group discussions.
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Written examinations, Assignments, Quiz
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Metal-based and non-metal based oxidations of-
Definition, generic modes, classification.
Covalent organocatalysis : Secondary amines via enamine, imine, imim ion, amidines, guanidines, Lewis base catalysis, nitrogen heterocyclic carbenes (NHC), synthesis, structure, catalysis-homo-and cross-benzoin condensation, Stetter reaction, hydrosilylation of styrenes, transesterification.
Noncovalent organocatalysis, hydrogen bonding catalysis, thiourea based catalysts, Diols- TADDOL.
Phosphorus containing organocatalysts: Triphenylphosphine, Binol-derived phosphoric acids, cyclic diphosphazanes, phosphonates.
e-Resources: