Analytical Chemistry

Paper Code: 
CHY-414
Credits: 
3
Contact Hours: 
45.00
Objective: 

Course Objectives:

This course will enable the students to -

  1. understand the concept of basic analytical techniques.

  2. discuss optical methods of analysis and chromatographic separation techniques.

 

Course Outcomes (COs):

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment

Strategies

Paper Code

Paper Title

CHY-414

 

 

 

 

Analytical Chemistry

 

 

 

 

 

The students will be able to –

 

CO114: understand basic concepts and applications of Potentiometry, Electrogravimetry, Coulometry and solvent extraction.

 CO115: explain  the applications of Polarography and Polarimetry methods in quantitative and qualitative estimation.

CO116: illustrate various optical methods of analysis such as Spectrophotocolorimetry, Atomic absorption spectroscopy and Flame Photometry

CO117: explain the significance of Rf value.

CO118: understand the principle and applications of various Chromatographic separation techniques like gas, liquid and ion exchange chromatography.
  • Interactive Lectures
  • Discussions
  • Tutorials
  • Problem solving

 
  • Presentations by Individual Student/ Group of Three Students
  • Class Tests at Periodic Intervals.
  • Written assignments
  • Semester End Examination

 

 

 

9.00
Unit I: 
Basic Analytical Techniques I

Potentiometry– Basic concepts and Applications in Acid-base titrations, oxidation-reduction titrations, precipitation titrations and complexometric titrations.

Electrogravimetry-Basic concept: current density, polarization, decomposition voltage, electrolysis at constant current and constant voltage and its basic applications.

Coulometry-Basic concepts: Constant current coulometry, constant potential coulometry, applications in neutralization titration, precipitation titration, oxidation- reduction titration.

 

9.00
Unit II: 
Basic Analytical Techniques II

Polarography – Introduction, polarographic measurement, half wave potential, residual current, migration current, diffusion current, Ilkovic equation, polarographic cell and dropping mercury electrode. Precautions and advantages, applications in quantitative and qualitative analysis.

Polarimetry- polarization of light, optical activity, angle of rotation, specific rotation, measurement of rotatory power (instrumentation), application of polarimetry in quantitative and qualitative analysis.

Solvent extraction- distribution law, process of extraction (liquid- liquid, solid-liquid), techniques for solvent extraction, classification and applications.

 

9.00
Unit III: 
Optical Methods of Analysis

Pre requisite: Lambert and Beer law, verification, derivation, signification of λmax and molar absorptivity, theory of fluorescence and phosphorescence.

Spectrophotocolorimetry: Single beam and double beam spectrophotometers, functions of the components, applications.

Atomic absorption spectroscopy: Principle, instrumentation, spectral interferences and chemical interferences in atomic absorption spectroscopy, applications in quantitative analysis (analysis of Zn2+, Cu2+ and Pb2+).

Flame photometry: Principle, instrumentation, interferences in flame photometry, applications in quantitative analysis. Comparison of atomic absorption and flame emission spectroscopy.

 

9.00
Unit IV: 
Chromatographic Separations I

General description and classification of chromatographic methods, thin layer, paper and column chromatographic techniques and their simple applications, Rf-values and their significance, elution in column chromatography, migration rates of solutes, band broadening and column efficiency, column resolution.

9.00
Unit V: 
Chromatographic Separations II

Principle, instrumentation, and applications of gas chromatography, high performance liquid chromatography and ion exchange chromatography.

References: 
  • Instrumental Methods of Analysis; Seventh Edition;Willard, Hobert H. et. al, CBS, 2004.
  • Analytical Chemistry, Seventh Edition,Christian, Gary D; John Willy New York, 2013.
  • Exploring Chemical Analysis, Fifth Edition;Harris, Daniel C; W.H.Freeman, New York, 2012.
  • Basic Concepts of Analytical Chemistry; Fourth Edition;Khopkar, S.M.,New AgeInternationalPvt Ltd, 2020.
  • Principles of Instrumental Analysis;Seventh Edition; Skoog, D.A., Holler F.J. and S.R. Crouch; Cengage Learning, USA, 2016.
  • Laboratory Hand Book of Chromatographic & Allied Methods; Mikes, O. &Chalmes, R.A;Halsted Press; 1979.
  • Analytical Chemistry-Methods of Separation; Ditts, R.V.; Van Nostrand, 1974.

 

Academic Year: 
2021-2022
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