ANALYTICAL CHEMISTRY I

Paper Code: 
CHY 214
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 

Course Objective(s):

This course will enable the students to –

  • acquaint with the basic principles of analytical and gravimetric techniques.
  • discuss the basic principles of volumetric analysis and chromatographic separation techniques.

Course Outcomes (COs):

Course Outcomes

Teaching learning strategies

Assessment

Strategies

On completion of this course, the students will be able to-

CO51:differentiate between different types of errors and distinguish between accuracy and precision. Calculate various types of deviations to express precision.

CO52:explain the basic concepts of volumetric analysis and apply them to demonstrate types of titrations and related calculations.

CO53:discuss principle, requirements and methods involved in different gravimetric analysis and identify various types of reagents used in gravimetric analysis.

CO54: purify different organic solids and liquids and check their purity.

CO55: understand the principle and applications of various chromatographic separation techniques like paper, thin layer and  column chromatography.
  • Class lectures
  • Tutorials
  • Group discussions
  • Use of models
  • Assertion and reasoning
  • Technology enabled learning
  • Peer learning

 
  • Oral and written examinations
  • Problem solving exercises
  • Assignments
  • Quiz
  • Efficient delivery using seminar presentations
  • Group activity
  • Multiple choice questions
  • Short answer type questions
  • Assertion and reasoning

 

 

9.00
Unit I: 
Basic Principles of Analytical Techniques

Data Analysis- significant figures, errors in chemical analysis, classification of errors (determinate indeterminate, systematic and random errors in chemical analysis with examples, absolute and relative errors),  accuracy and precision, minimisation of errors, distribution of random errors, normal error curve, statistical analysis – mean and standard deviation, relative standard deviation coefficient of variance, sampling in analysis, rejection of results, presentation of data.

 

9.00
Unit II: 
Basic Principles of Volumetric Analysis

Theoretical aspects- classification and primary requirements of titrations.
Acid-base titrations- basic principle, neutralisation indicators – types, theories of indicators, choice of indicators, titration curves and applications.
Redox titrations- principle, indicators, and applications of permangnatometry, dichromatometry, iodometry titrations
Complexometric titration- reactions and properties of EDTA, types of EDTA titrations, selectivity (masking and demasking) in complexometry, metal ion indicators and applications.
Precipitation titration- principle, types of titrations (Mohr’s, Volhard’s, Fajan’s), indicators and applications.

9.00
Unit III: 
Gravimetric Methods of Analysis

Requirements of gravimetry- Properties of precipitates and precipitating regents, particle size and filterability of precipitates, colloidal and crystalline precipitates, co-precipitation and post-precipitation, washing, drying and ignition of precipitates, precipitation in homogenous media, principles of gravimetric estimation of chloride, zinc, iron and aluminium.
Use of organic reagents in gravimetric analysis- dimethylglyoxime, 8-hydroxyquinoline, anthranilic acid, cupferron.          

 

9.00
Unit IV: 
Purification Techniques

Purification Techniques for solid organic compounds-crystallization, fractional crystallization, sublimation, sublimation under reduced pressure, solvent extraction
Purification Techniques for liquids-simple distillation, fractional distillation, distillation under reduced pressure, steam distillation, criteria of purity

 

9.00
Unit V: 
Chromatographic Separations

General description and classification of chromatographic methods, thin layer, paper and column chromatographic techniques and their simple applications,  Rf

-values and their significance, elution in column chromatography, migration rates of solutes, band broadening and column efficiency, column resolution.

 

Essential Readings: 
  • Analytical Chemistry, Second Edition; D. C. Dash; PHI Learning Private Limited, New Delhi, 2016.
  • Basic Concepts of Analytical Chemistry, Fourth Edition; S. M. Khopkar; New Age International Pvt Ltd. Publishers, 2020.

 

References: 

SUGGESTED READINGS

  • Instrumental Methods of Analysis, Seventh Edition; H. H. Willard, Jr. L. L. Merritt, J. A. Dean, F. A. Settle; CBS Publishers and Distributors, 2004.
  • Analytical Chemistry, Seventh Edition; G. D. Christian, John Wiley & Sons, New York, 2013.
  • Principles of Instrumental Analysis, Seventh Edition; D. A. Skoog, F. J. Holler and S. R. Crouch; Boston, Mass.: Cengage Learning, USA, 2016.

       e-RESOURCES:

 

Academic Year: 
2022-2023
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