Biology for Chemists

Paper Code: 
25CHY125 (B)
Credits: 
2
Contact Hours: 
30.00
Max. Marks: 
100.00
Objective: 

understand the basic processes which link the biological systems with the chemical systems and to provide them with the basic knowledge and insight about the three-dimensional (3D) structure of macromolecules (protein and nucleic acids) and the relationship between their structure and function.

 

 

Course Outcomes: 

Course

Learning outcome

(at course level)

Learning and Teaching Strategies

Assessment Strategies

Course Code

Course

Title

 

25CHY125 (B)

 

Biology for Chemists (Theory)

CO31: Differentiate between prokaryotic and eukaryotic cells and describe the structure and functions of important cell organelles and discuss Krebs cycle and oxidative phosphorylation.

CO32: Illustrate the structure and function of amino acids and proteins.

CO33: Explain classification, structure and functions of different types of carbohydrates and differentiate between simple and complex carbohydrates.

CO34: Discuss Structure, nomenclature and functions of lipids, and differentiate between saturated and unsaturated fatty acids. Elaborate the process of α & β-oxidation.

CO35: Classify purines and pyrimidines, discuss the structure, types and different models of DNA and RNA.

CO36: Contribute effectively in course-specific interaction.

Approach in teaching:

Interactive lectures, tutorials, group discussions and e-learning.

 

Learning activities for the students:

Peer learning, e- learning, problem solving through tutorials and group discussions.

 

 

Written examinations,

Assignments, Quiz

 

 

6.00
Unit I: 
Concept of Cell

Origin of life: Prokaryotes and eukaryotes, difference between plant and animal cell, hierarchy of molecular organization of living systems, a brief concept of cell organelles and their functions- nucleus, plasma membrane, chloroplast, Golgi bodies, endoplasmic reticulum, lysosomes, ribosomes and mitochondria, ATP synthesis, substrate level phosphorylation like glycolysis and Kreb’s cycle and oxidative level phosphorylation.

 

 

7.00
Unit II: 
Amino Acids & Proteins

Introduction, classification, optical isomerism, chemical properties, acid-base properties- peptide bond formation and properties, protein structure- primary, secondary, tertiary & quaternary structures, denaturation of proteins, Ramachandran plot, determination of primary structure - sequencing strategies, N-terminal and C-terminal sequencing, synthesis of amino acids by reductive amination, GS-GOGAT system and transamination.

Enzymes: Introduction, classification of enzymes, mechanism of enzyme action, enzyme kinetics, Michaelis – Menten equation and enzyme inhibition.       

6.00
Unit III: 
Carbohydrates

Classification, structure and functions of monosaccharides, disaccharides, polysaccharides-starch, cellulose, glycogen, chitin and pectin, glycoconjugates, proteoglycans, glycoproteins and glycolipids

5.00
Unit IV: 
Lipids

Structure, sources, nomenclature and functions of lipids, saturated and unsaturated fatty acids, classification- simple, compound and derived lipids (steroids and cholesterol), synthesis of long chain fatty acids, α-oxidation, β-oxidation.

 

6.00
Unit V: 
Nucleic Acids

Purines and Pyrimidines: Structures of purine and pyrimidine bases, nucleosides and nucleotides.

DNA, Double helical structure of DNA(Watson and Crick model) , types of DNA, A, B, C and Z forms, replication.

RNA, RNA structure and its types- rRNA, mRNA, and tRNA, ribozymes, differences between DNA & RNA

 

Essential Readings: 
  1. Lehninger Principles of Biochemistry, International Edition, Seventh Edition; D. L. Nelson,       M. Cox; W.H. Freeman, 2017.
  2. Biochemistry, Fourth Edition; D. Voet; John Wiley and Sons, 2011.

 

References: 
  1. Biochemistry, Ninth Edition; L. Stryer; W.H. Freeman and Company, 2019
  2. Biochemistry, First Indian Reprint; J. D. Rawn; Tanima Publishing Corporation, New Delhi,       2004.
  3. Outline of Biochemistry, Fifth Edition; E.E. Conn and P.K. Stumpf; John Wiley and Sons       Inc., New Delhi, 2006.

 

e- Resources:

  1. https://egyankosh.ac.in/bitstream/123456789/16222/1/Unit-1.pdf
  2. https://egyankosh.ac.in/bitstream/123456789/71691/1/unit-1.pdf
  3. https://egyankosh.ac.in/bitstream/123456789/15773/1/Unit-2.pdf
  4. https://epgp.inflibnet.ac.in/epgpdata/uploads/epgp_content/S000002BI/P000983/M01688      2/ET/1491301143P05M05Lipids-TypesI.pdf
  5. https://epgp.inflibnet.ac.in/epgpdata/uploads/epgp_content/S000002BI/P000983/M01689      8/ET/1491302127P05M21Lipids-OxidationI.pdf

 

 

 

Academic Year: