BIOLOGY FOR CHEMISTS

Paper Code: 
CHY 125 B
Credits: 
2
Contact Hours: 
30.00
Max. Marks: 
100.00
Objective: 

Course Objective(s):

This course will enable the students to –

understand the basic processes which link the biological systems with the chemical systems and to provide them with the basic knowledge and insight about the three-dimensional (3D) structure of macromolecules (protein and nucleic acids) and the relationship between their structure and function.

 

Course Outcomes (COs): 

Course Outcomes

Teaching Learning Strategies

Assessment Strategies

On completion of this course, the students will be able to-

CO26:describe the function of several important proteins and relate their function to the structure.

CO27:identify the chemical elements of carbohydrates and the difference between simple sugars and complex carbohydrates. 

CO28:discuss the relationship between cellular activities and biological responses. 

CO29:outline cell metabolism, chemical composition, physiochemical and functional organization of organelles.

CO30:illustrate the different composition and roles of nucleic acids in the cell and their interactions with each other and analyze contemporary approaches and techniques used in modern cell and molecular biology. 
  • Interactive lectures
  • Tutorials
  • Group discussions
  • Use of models
  • Digital learning
  • Problem solving sessions
  • Assertion and Reasoning

 
  • Oral and written examinations
  • Assignments
  • Quiz

 

 

 

 
6.00
Unit I: 
Concept of Cell

Origin of life: Prokaryotes and eukaryotes, difference between plant and animal cell, hierarchy of molecular organization of living systems, a brief concept of cell organelles and their functions- nucleus, plasma membrane, chloroplast, Golgi bodies, endoplasmic reticulum, lysosomes, ribosomes and mitochondria, ATP synthesis, substrate level phosphorylation like glycolysis and Kreb’s cycle and  oxidative level phosphorylation.

9.00
Unit II: 
Amino Acids & Proteins

Introduction, classification, optical isomerism, chemical properties, acid-base properties- peptide bond formation and properties, protein structure- primary, secondary, tertiary & quaternary structures, denaturation of proteins, Ramachandran plot, determination of primary structure - sequencing strategies, N-terminal and C-terminal sequencing, synthesis of amino acids by reductive amination, GS-GOGAT system and transamination.

Enzymes: Introduction, classification of enzymes, mechanism of enzyme action, enzyme kinetics, Michaelis – Menten equation and enzyme inhibition.

4.00
Unit III: 
Carbohydrates

Classification, structure and functions of monosaccharides, disaccharides, polysaccharides-starch, cellulose, glycogen, chitin and pectin, glycoconjugates, proteoglycans, glycoproteins and glycolipids.

5.00
Unit IV: 
Lipids

Structure, sources, nomenclature and functions of lipids, saturated and unsaturated fatty acids, classification- simple, compound and derived lipids (steroids and cholesterol), synthesis of long chain fatty acids, α-oxidation, β-oxidation.

6.00
Unit V: 
Nucleic Acids

Purines and Pyrimidines: Structures of purine and pyrimidine bases, nucleosides and nucleotides.

DNA, Double helical structure of DNA(Watson and Crick model) , types of DNA, A, B, C and Z forms, replication.

RNA, RNA structure and its types- rRNA, mRNA, and tRNA, ribozymes, differences between DNA & RNA.

Essential Readings: 
  • Lehninger Principles of Biochemistry, International Edition, Seventh Edition; D. L. Nelson, M. Cox; W.H. Freeman, 2017.
  • Biochemistry, Fourth Edition; D. Voet; John Wiley and Sons, 2011.
References: 

SUGGESTED READINGS:

  • Biochemistry, Ninth Edition; L. Stryer; W.H. Freeman and Company, 2019
  • Biochemistry, First Indian Reprint; J. D. Rawn; Tanima Publishing Corporation, New Delhi, 2004.
  • Outline of Biochemistry, Fifth Edition; E.E. Conn and P.K. Stumpf; John Wiley and Sons   Inc., New Delhi, 2006.

 

e- RESOURCES:

Academic Year: 
2023-2024
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