Coming soon
Biomolecules
This course will enable the students to
· understand the fundamentals related to the electrochemical process and their applications.
· gain an in-depth knowledge of theories of chemical kinetics and mechanism of catalyzed reactions.
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Course |
Learning Outcome (at course level) |
Learning and Teaching Strategies |
Assessment Strategies |
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Course Code |
Course Title |
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25DCHY515(A) |
Biomolecules (Theory)
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CO103: Describe structural configuration, their synthesis & reactions of nucleic acids. CO104: Discuss the theories of enzyme kinetics, the mechanisms of enzyme catalysis, and the mechanisms of enzyme regulation in the cell. CO105: Explain the chemistry of lipids. CO106: Comprehend the concept of energy in biosystems. CO107: Learn about a variety of drug classes and their pharmacological actions. CO108: Contribute effectively in course-specific interaction. |
Approach in teaching: Interactive lectures, tutorials, group discussions and e-learning.
Learning activities for the students: Peer learning, e-learning, problem solving through tutorials and group discussions.
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Written examinations, assignments and quiz.
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Components of nucleic acids, nucleosides and nucleotides, structure, synthesis and reactions of: adenine, guanine, cytosine, uracil and thymine, structure of polynucleotides.
α-Amino Acids: Synthesis, ionic properties and reactions, zwitterions, pKa values, isoelectric point and electrophoresis.
Study of peptides: Determination of their primary structures-end group analysis, methods of peptide synthesis: synthesis of peptides using N-protecting, C-protecting and C-activating groups: solid-phase synthesis.
Proteins: Classification and structure.
Introduction, classification and characteristics of enzymes, salient features of active site of enzymes,
mechanism of enzyme action (taking trypsin as example), factors affecting enzyme action, coenzymes and cofactors and their role in biological reactions, specificity of enzyme action (including stereospecificity), enzyme inhibitors and their importance, phenomenon of inhibition (competitive, uncompetitive and non-competitive inhibition including allosteric inhibition).
1. Biochemistry, Sixth Edition; J.M. Berg, J.L. Tymoczko, & L. Stryer; W.H. Freeman and Co., 2006.
2. Principles of Biochemistry, Fourth Edition; D.L. Nelson, M.M. Cox, & A.L. Lehninger; W.H. Freeman and Co., 2009.
Suggested Readings:
1. Harper’s Illustrated Biochemistry; XXVIII edition; R.K. Murray, D.K. Granner, P.A. Mayes, & V.W. Rodwell, Lange Medical Books/ McGraw-Hill, 2009.
e-Resources:
1. https://www.slideshare.net/mmravagnan/powerpoint-enzymes (Unit II)
2. https://epgp.inflibnet.ac.in/Home/ViewSubject?catid=MNhNzp1RQlU+6LM40KjY1Q== (Unit I and III)
