Laboratory Course

Organic Chemistry

Synthesis

Synthesis (Greenmethods)                                                                                      

a)  Aromatic Electrophilic Substitution

i)  Acetylation – Acetylation of aniline/salicylic acid.

ii)  Nitration - Preparation of 4-nitrosalicylic acid

ii) Bromination - Preparation of p-bromoacetanilide

b)  Halogen Addition to C=C bond

i)  Bromination of Trans Stilbene

c) [4+2] cycloaddition Reaction

i)  Diel’s Alder reaction between furan and maleic acid

d) Pechmann Condensation for Coumarin synthesis

i) Clay catalysed solid state synthesis of 7-hydroxy -4-methyl coumarin

e) Diazotization/coupling

i)  Preparation of methyl orange

Spectroscopy: Interpretation of IR and NMR spectra of simple organic compounds (ethanol, 1-propanol, 2-propanol, methylethanoate, ethyl acetate,stilbene, ethyl acetate, propanone etc).

QuantitativeAnalysis                                                                                                         

1. To determine the neutralization equivalent of the acid.
2. Estimation of glucose by Fehling’s solution/Benedict’s solution method.
3. Estimation of saponification value of oil.