Organic Chemistry Lab I

Paper Code: 
24CHY227
Credits: 
3
Contact Hours: 
90.00
Max. Marks: 
100.00
Objective: 

This course will enable the students to-

acquire ample training in handling basic chemical laboratory instruments, develop quantitative and qualitative skills to use the basic techniques involved in synthetic organic chemistry.

 

Course Outcomes (COs):

Course

Learning outcome

(at course level)

Learning and Teaching Strategies

Assessment Strategies

Course Code

Course

Title

 

24CHY227

 

Organic Chemistry Lab I

 (Practical)

CO88:   pply suitable techniques to separate and identify organic compounds from the given mixture.

CO89:    Recrystallize the separated compounds and the confirmation of the purity through TLC.

CO90:    Perform the experiments for the determination of the functional groups and samples quantitatively.

CO91: Compile and report the results efficiently and develop communication skills.

CO92: Contribute effectively in course-specific interaction.

Approach in teaching:

Laboratory instructions and

Demonstrations.

 

Learning activities for the students:

Peer learning, hands-on-learning,

interpretation of data, record writing and learning through virtual labs.

Conduction of Experiments, Lab Records, Viva Voce, Quiz

 

Unit I: 

Basic Techniques Involved in Synthetic Organic Chemistry

  • Different types of glasswares.
  • Filtration.
  • Distillation (distillation at atmospheric pressure, steam distillation, fractional distillation and distillation at reduced pressure).
  • Recrystallization and melting point correction.
  • Use of decolorizing carbon.
  • Thin layer chromatography.

 

Qualitative Analysis

Separation, purification and identification of components of a mixture of two organic compounds (one liquid and one solid or two solids) using TLC for checking the purity of separated compounds.

 

Quantitative Analysis

  • Determination of the percentage and number of hydroxyl groups in an organic compound by acetylation method.
  • Estimation of amines/phenols using bromate bromide solution.
  • Determination of iodine number and saponification value of an oil sample

 

Demonstration Exercise

  • Estimation of sulphur by messenger or fusion method.
  • Estimation of nitrogen by Kjeldahl’s method.

 

Scheme of Examination

 

The duration of examination will be 6 hrs.

The following exercise will be set in the examination

Organic Mixture Analysis                                               30 marks

Quantitative analysis                                                    25 marks

Viva                                                                            15 marks

      Total                                                                         70 marks

                                                                 

  1. Organic Mixture analysis

This exercise carries 30 marks for the identification of two organic compounds. 6 marks are reserved for the proper selection of separation technique, four marks for proper reporting of result and rest of the 20 marks are kept for the identification of two organic compounds (10 marks each)

 

  1. Physical properties: colour, state, odour                         ½ marks
  2. Solubility                                                                       ½ marks
  3. Aliphatic/Aromatic                                                          ½ marks
  4. Element(s) detection                                                     2 marks
  5. Functional group(s), M.P./B.P.                                        3 marks
  6. Confirmatory test                                                          1 marks
  7. Derivative- procedure & M.P.                                         2½ marks

 

Out of two organic compounds, one compound will be so given that its derivative can be obtained under the prevailing conditions of the laboratory.

 

  1. Quantitative analysis

The exercise carries 20 marks. Distribution is as follows:

 

Theory and procedure                           5 marks

Preparation of solutions                         4 marks

Observation                                          4 marks

Calculation                                            6 marks

Result                                                   6 marks

   

  1. Viva

Oral questions shall generally be asked over the work assigned to the candidate. The purpose is to find out as to what extent the candidate has understanding the basic principles of chemistry.

 

Essential Readings: 
  1. Vogel’s Textbook of Practical Organic Chemistry, Fifth Edition; B.S. Furniss, A.J. Hannaford,
  2. P.W.G. Smith, A.R. Tatchell; Adission – Wesley Longman Ltd. England, 2015.
  3. Practical Organic Chemistry, Fourth Edition; F.C. Mann, B.C. Saunders; Pearson Education Ltd., New Delhi, 2013.

 

References: 

1.Advanced Practical Organic Chemistry, J. Leonard, B. Lygo and G. Procter; Third Edition; CRC Press,2013.

 

e-Resources:

  1.   https://www.researchgate.net/publication/332029217_Qualitative_analysis_of_organic_mixture_Binary_and_Ternary_chart_for_MSc_organic_students (Separation of organic mixture)
  2. https://labmonk.com/determination-of-saponification-value-of-the-given-oil-fat#:~:text=Principle%3A%20Saponification%20value%20is%20defined,titrated%20against%20a%20standard%20acid. (Determination of saponification value )
  3. https://www.youtube.com/watch?v=ll3XnKvIX1o (Estimation of phenols)
  4. https://vlab.amrita.edu/?sub=2&brch=294&sim=1551&cnt=1 (Kjeldahl’s method)
  5. http://sulphur.atomistry.com/estimation.html (Estimation of sulphur)
Academic Year: 
2024-2025
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