Organic Chemistry Lab II

Paper Code: 
CHY-327
Credits: 
3
Contact Hours: 
90.00
Max. Marks: 
100.00
Objective: 

Course Objectives :

The course aims to provide knowledge of synthesis by conventional and non-conventional methods, handling of hazardous chemicals, and to enhance learning of physical and spectroscopic techniques.

Course Outcomes (COs):                                                                                                   

COURSE

Learning outcomes (at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

CHY 327

Organic Chemistry Lab II

 The students will be able to-

 

CO121- characterize organic molecules by physical and spectroscopic methods including mp, bp, IR, NMR and chromatography

CO122- demonstrate and apply common laboratory techniques, including refluxing, distillation, steam distillation, recrystallization, vacuum filtration, extraction, thin layer chromatography, column chromatography in the specific synthesis etc.

CO123- employ spectrophotometric techniques for the estimations of prescribed biomolecules.

Interactive Lectures

 

Discussions

 

Tutorials

 

Written test

 

Google quiz

 

Viva-voce

 

Semester End Exam (Practical as well as written test followed by Viva-voce).
 

 

Unit I: 

Synthesis (Green Methods / Conventional Methods)

a. One step synthesis

    · Aldol condensation (Synthesis of dibenzal propanone)

    · Acetylation (synthesis of acetanilide from aniline)

    · Pechmann Condensation for Coumarin synthesis (Clay catalyzed solid state                synthesis of 7-hydroxy -4-methyl coumarin)

     · Bromination of phenol

b. Two step synthesis (any three)

     · Benzoin → benzil → benzilic acid

     · Benzophenone → benzpinacol → benzpinacolone

     · Acetanilide → p-bromoacetanilide → p-bromoaniline

      · Acetanilide → p-nitroacetanilide → p-nitroaniline

      · Resorcinol → flouroscein → eosin

      · Phthalicanhydride → phthalimide → anthranilicacid

Extraction of Organic Compounds from Natural Resources (any three)

      · Isolation of caffeine from tea leaves.

      · Isolation of casein from milk.

      · Isolation of lactose from milk.

      · Isolation of nicotine dipicrate from tobacco.

Spectroscopy

Identification of organic compounds (with emphasis on isomeric studies andcalculation of % ratio of tautomers) by the spectral analysis.

 

Spectrophotometric Estimations (any three)

· Protein

· Carbohydrate

· Cholesterol

· Phosphate

Ascorbic acid

References: 
  • Vogel’s Textbook of Practical Organic Chemistry; Fifth Edition, B.S. Furniss, A.J. Hannaford, P.W.G. Smith, A.R. Tatchell; Addison – Wesley Publishing Company, 2014.
  • Practical Organic Chemistry; Fourth Edition; F.C. Mann and B.C. Saunders; Pearson Education, New Delhi, 2013.
  • Advanced Practical Organic Chemistry; J. Leonard, B. Lygo and G. Procter; Third Edition; CRC Press, 2013.
Academic Year: 
2021-2022
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