Organic Chemistry Lab II

Synthesis (Green Methods / Conventional Methods)

1. One step synthesis

•    Aldol condensation (Synthesis of dibenzal propanone)

• Acetylation (synthesis of acetanilide from aniline)
• Pechmann Condensation for Coumarin synthesis (Clay catalysed solid state synthesis of 7-hydroxy -4-methyl coumarin)
• Bromination of phenol

2. Two step synthesis (any three)

• Benzoin → benzil → benzilic acid
• Benzophenone → benzpinacol → benzpinacolone
• Acetanilide → p-bromoacetanilide → p-bromoaniline
• Acetanilide → p-nitroacetanilide → p-nitroaniline
• Resorcinol → flouroscein → eosin
• Pthalic anhydride → pthalimide → anthranilic acid                  

Extraction of Organic Compounds from Natural Resources (any three)

• Isolation of caffeine from tea leaves.
• Isolation of casein from milk.
• Isolation of lactose from milk.
• Isolation of nicotine dipicrate from tobacco.

Spectroscopy

Identification of organic compounds (with emphasis on isomeric studies and calculation of % ratio of tautomers) by the spectral analysis.

Spectrophotometric Estimations (any three)

• Protein
• Carbohydrate
• Cholesterol
• Phosphate
• Ascorbic acid