Supramolecular Chemistry and Spectroscopy

Definition and development of supra molecular chemistry, nature of supramolecular interactions (ion pairing, ion-dipole, dipole-dipole, dipole-induced dipole and ion-induced dipole, van der Waals or Dispersion, hydrogen bonding, cation-π, anion-π,  closed shell, π-π stacking).

Classification of host-guest compounds, pre-organisation and complementarity: thermodynamic and kinetic effects.

Cation Binding: Complexation by crown ether, cryptands (spherical and tetrahedral recognition), spherands, lariat ethers and podands. Recognition of ammonium ions.Synthesis: Template effect and high dilution. Biological significance: Valinomycin and nonactin.

Anion Binding: Basic concepts of anion binding,cyclophanes and guanidinium-based receptors,neutral receptors: zwitterions, amide-based receptors. Biological significance: Phosphate and sulphate binding properties. Binding and recognition of neutral molecules.

Coreceptor molecules and multiple recognition: dinuclearandpolynuclear metal ion cryptates,      linear recognition of molecular length by ditopic coreceptors, heterotopic coreceptors: Cyclophane  receptors, amphiphilic receptors, large molecular cages, multiple recognition in metalloreceptors.

Transport processes and carrier design: Cation, anion and coupled transport process.

Supramolecular devices: Supramolecular photochemistry, supramolecular electronic, ionic and switching devices.

Supramolecular catalysis: Supramolecular metallocatalysis, co-catalysis, bimolecular and abiotic catalysis.

Biochemical self assembly, self assembly with covalent modification, template effects in synthesis, a thermodynamic model, cooperativity and extended site binding model, probability of self assembly, self assembling coordination compounds(design and notation, supramolecular cube, molecular squares and boxes.

UV: Visible molecular absorption spectrometry (instrumentation and application).

NMR Spectroscopy: Theory and applications of ¹H and ¹³C   NMR spectroscopy.

Mass & IR Spectroscopy: Theory and applications.

Structural elucidation by UV, IR, NMR & Mass Spectra.