ADVANCED INORGANIC CHEMISTRY

Paper Code: 
CHY 601
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 

Course Objective(s):

This course will enable the students to –

  • appreciate the vitality of metal ions in biosystems and the importance of organic and inorganic polymers
  • Understand the basics of nuclear chemistry, calculate binding energy, mass defect, half-life of radioactive elements and age of fossils, rocks etc.
  • develop a knowledge of stability and reaction mechanism in metal complexes
  • explain bonding in carbonyls and nitrosyls

 

Course Outcomes (COs):

Course Outcomes

Teaching learning strategies

Assessment

Strategies

On completion of this course, the students will be able to-

CO79: define, classify and name various organometallic compounds. Calculate valence electron count (18-electron). Discuss the preparation, properties, bonding and applications of organometallic compounds of some simple metals.

CO80: interpret the structure and bonding involved in metal carbonyls and metal nitrosyls.

CO81: differentiate between bulk and trace elements, identify the importance of metal ions in biological systems, describe the structure and functions of different metalloenzymes and explain the mechanism of photosynthesis.

CO82: explain thermodynamic with kinetic stability and compare between inert and labile complexes.

CO83: Discuss SN2 mechanism in square planar complexes and apply the concept of trans effect to identify the cis and trans isomers.

CO84: compare the types of nuclear models, calculate the binding energy, half-life, the age of an object (radiochemical dating). Explain the functions of the major components of a nuclear reactor. Differentiate the artificial and natural radioactivity and discuss the hazards of radiation and safety measures.

 
  • Class lectures
  • Tutorials
  • Group discussions
  • Use of models
  • Assertion and reasoning
  • Technology enabled learning
  • Peer learning

 
  • Oral and written examinations
  • Problem solving exercises
  • Assignments
  • Quiz
  • Efficient delivery using seminar presentations
  • Group activity
  • Multiple choice questions
  • Short answer type questions
  • Assertion and reasoning

 
 

 

9.00
Unit I: 
Organometallic Chemistry

Definition, nomenclature and classification of organometallic compounds, general characteristics, preparation, properties, bonding and applications of alkyls and aryls of Li, Al, Hg, Sn and Ti, metal ethylenic complex – Zeise’s salt (brief idea), hydrogenation and polymerization of alkene by organotransition metal complex (an elementary concept).

 

9.00
Unit II: 
Metal Carbonyls and Nitrosyls

Introduction to π acceptor ligands, definition, classification, general methods of preparation, properties, 18 electron rule and EAN concept, structure and nature of bonding in metal carbonyls (mononuclear carbonyls only), metal nitrosyls- preparation, structure and nature of bonding.

 

9.00
Unit III: 
Bio-inorganic Chemistry

The biological role of metal ions- Na & K (sodium potassium pump), Ca (general idea of calcium binding proteins and functions), Mg (structure of chlorophyll and its role in photosynthesis- PS I and PS II), Fe (haemoglobin and myoglobin- structure, mechanism of oxygen binding and Bohr effect), Zn (carboxypeptidase and carbonic anhydrase- structure and functions).

9.00
Unit IV: 
Thermodynamic and Kinetic Stability of Metal Complexes

Kinetic v/s thermodynamic stability, stepwise and overall formation constants, labile and inert complexes, factors affecting the stability of complexes, trans-effect- theories and its uses, mechanism of substitution reactions in square planar complexes.

9.00
Unit V: 
Nuclear Chemistry

Nuclear models -elementary idea of Shell model and Liquid drop model, natural and artificial radioactivity, transmutation of elements, radioactive disintegration series, half-life of radio elements, nuclear reactions- fission, fusion and spallation, nuclear reactors and power generation, counters- Geiger-Muller counter and Scintillation counter (elementary idea), applications of radioactive isotopes in medicines, agriculture, in determination of age of rocks and minerals, in radio carbon dating.
Self Study: Atomic nucleus, nuclear particles, nuclear forces, quantitative idea of stability of nucleus, packing fraction, binding energy and mass defect, mode of decay, Soddy-Fajan’s displacement law (group displacement law),

 

Essential Readings: 
  • Essentials of Nuclear Chemistry, Fourth Edition; H.J. Arnikar; New Age International(P) Ltd., New Delhi, 2011.
  • Organometallic Chemistry: A Unified Approach, Second Edition; R.C. Mehrotra and A. Singh; New Age International Private Limited, New Delhi, 2000.
  • Inorganic Chemistry (Principle of Structure and Reactivity), Fourth Edition; J. E Huheey, E. A. Keiter, R. L. Keiter; Pearson India, New Delhi, 2013.
  • Principles of Inorganic Chemistry, Thirty Third Edition; B.R. Puri, L.R. Sharma, K.C. Kalia; Vishal Publishing Co., Delhi, 2020.

References: 

SUGGESTED READINGS:

  • Inorganic Chemistry, Fifth Edition; Gary L. Miessler and Donald A. Tarr; Pearson Education Inc., Singapore, 2013.
  • Principles of Bioinorganic Chemistry, First Edition; S. J. Lippard, J.M. Berg; Panima Publishing Corporation, New Delhi, 2005.
  • Inorganic Chemistry, Seventh International Edition; M. Weller, T. Overton, J. Rourke, F. Armstrong; Oxford University Press, New York, 2018.

e-RESOURCES:

 

Academic Year: 
2022-2023
  • Printer-friendly version
  • PDF version