BIOLOGY FOR CHEMISTS I

Paper Code: 
CHY 114 B
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 

Course Objective(s):

This course will enable the students to -

  • understand the structure and function of various cell organelles.
  • learn about biological membrane and transport mechanism across the cell membrane and analyse its regulation
  • interpret and compare the properties of the fatty acids and outline the synthesis of long chain fatty acids.

Course Outcomes (COs):

Course Outcomes

Teaching learning strategies

Assessment

Strategies

On completion of this course, the students will be able to-

CO25: relate the structure and function of some simple cell organelles.

CO26: develop the understanding of catalysis and use of energy by cells, the structures and purposes of basic components of prokaryotic and eukaryotic cell

CO27: explain the basis of selective membrane permeability and the distinguishing features of substances that can move across freely and those that require protein transporters.

CO28: recognise the structure of various types of amino acids and proteins and also explain the factors affecting protein denaturation

CO29: distinguish between monosaccharides, disaccharides, and polysaccharides and describe the functions of carbohydrates.
  • Class lectures
  • Tutorials
  • Group discussions
  • Use of models
  • Assertion and reasoning
  • Technology enabled learning
  • Peer learning

 

 

 

• Oral and written examinations
Problem solving exercises

  • Assignments
  • Quiz
  • Efficient delivery using seminar presentations
  • Group activity
  • Multiple choice questions
  • Short answer type questions
  • Assertion and reasoning

 

 

9.00
Unit I: 
Basics of Cell Biology (structure & function)

Discovery of cell and cell theory, comparison between plant and animal cells, cell wall, plasma membrane, modification of plasma membrane and intracellular junctions, cytoskeleton, protoplasm, mitochondria, chloroplast, ER, Golgi complex, lysosome, endosome and microbodies, ribosome, centriole, nucleus
Biogenesis of Cellular organelles – biosynthesis of mitochondria, chloroplast, ER,
Golgi complex, biosynthetic process in ER and Golgi apparatus, protein synthesis and folding in the cytoplasm, degradation of cellular components

 

9.00
Unit II: 
Structure and function of prokaryotic cell & its components

The Slime and the cell wall of bacteria containing peptidoglycan and related molecules, outer membrane of Gram-negative bacteria, cytoplasmic membrane, mesosomes, carboxysomes, sulfur granules, glycogen, polyphosphate bodies, fat bodies, gas vesicles, endospores, exospores, cysts, , cytoskeleton filaments.

9.00
Unit III: 
Membrane structure & transport

Models of membrane structure, membrane lipids, proteins and carbohydrate, solute transport by Simple diffusion, facilitated diffusion and Active transport, water and ion transport

 

9.00
Unit IV: 
Proteins & Nucleic Acids

Proteins- structure of amino acid, types of amino acid (essential and nonessential), structure of zwitterions, peptide bond, structure of proteins- primary, secondary-α helix and β pleated sheets, tertiary and quaternary structure, denaturation of proteins.
Nucleic acids- Double helical structure of DNA, types of DNA -A, B, C and Z forms, replication.
RNA- RNA structure and its types- rRNA, mRNA, and tRNA 

 

 

9.00
Unit V: 
Carbohydrates & Lipids

Carbohydrates-classification, structure and functions of monosaccharides, disaccharides, polysaccharides - starch, cellulose, glycogen, chitin and pectin, glycoconjugates- proteoglycans, glycoproteins and glycolipids.
Lipids-structure and functions of lipids, saturated and unsaturated fatty acid, classification- simple compound and derived lipids (steroids and cholesterol), synthesis of long chain fatty acids, α-oxidation and β-oxidation.

 

Essential Readings: 
  • Lehninger Principles of Biochemistry, Seventh Edition; David L. Nelson, Michael M. Cox; W H Freeman, New York, 2017.
  • Biochemistry, Fourth Edition; Voet and Voet; John Wiley and Sons Inc., New York, 2010.

 

References: 

SUGGESTED READINGS:

  • Biochemistry,  Ninth Edition; Jeremy M. Berg , Lubert Stryer , John Tymoczko , Gregory Gatto ;WH Freeman, New York ,2019.
  • Biochemistry, First Indian Reprint; J. David Rawn, Panima Publishing Corporation, New Delhi, 2004.
  • Outline of Biochemistry, Fifth Edition; E.E. Conn and P.K. Stumpf; Wiley India Pvt Ltd., New Delhi, 2006.

e-RESOURCES:

 

 

Academic Year: 
2022-2023
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