Organic Chemistry Lab II

Paper Code: 
CHY 327
Credits: 
3
Contact Hours: 
90.00
Max. Marks: 
100.00
Objective: 

Course Objectives :

The course aims to provide knowledge of synthesis by conventional and non-conventional methods, handling of hazardous chemicals, and to enhance learning of physical and spectroscopic techniques.

Course Outcomes (Cos):                                                                                                            

COURSE

Learning outcomes (at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

CHY 327

Organic Chemistry Lab II

 The students will be able to-

CO114- characterize organic molecules by physical and spectroscopic methods including mp, bp, IR, NMR and chromatography

CO115- demonstrate and apply common laboratory techniques, including refluxing, distillation, steam distillation, recrystallization, vacuum filtration, extraction, thin layer chromatography, column chromatography in the specific synthesis etc.

CO116- use spectrophotometric techniques for the estimations of some biomolecules.

Interactive Lectures

 

Discussions

 

Tutorials

 

Written test

 

Google quiz

 

Viva-voce

 

Semester End Exam (Practical as well as written test followed by Viva-voce).
 

 

Unit I: 

Synthesis (Green Methods / Conventional Methods)

  1. One step synthesis
  •    Aldol condensation (Synthesis of dibenzal propanone)
  • Acetylation (synthesis of acetanilide from aniline)
  • Pechmann Condensation for Coumarin synthesis (Clay catalyzed solid state synthesis of 7-hydroxy -4-methyl coumarin)
  • Bromination of phenol

 

  1. Two step synthesis (any three)
  • Benzoin → benzil → benzilic acid
  • Benzophenone → benzpinacol → benzpinacolone
  • Acetanilide → p-bromoacetanilide → p-bromoaniline
  • Acetanilide → p-nitroacetanilide → p-nitroaniline
  • Resorcinol → flouroscein → eosin
  • Phthalicanhydride → phthalimide → anthranilicacid

 

 

Extraction of Organic Compounds from Natural Resources (any three)

  • Isolation of caffeine from tea leaves.
  • Isolation of casein from milk.
  • Isolation of lactose from milk.
  • Isolation of nicotine dipicrate from tobacco.

 

Spectroscopy

Identification of organic compounds (with emphasis on isomeric studies and calculation of % ratio of tautomers) by the spectral analysis.

 

 

Spectrophotometric Estimations (any three)

  • Protein
  • Carbohydrate
  • Cholesterol
  • Phosphate
  • Ascorbic acid

 

References: 
  • Vogel’s Textbook of Practical Organic Chemistry; Fifth Edition, B.S. Furniss, A.J. Hannaford, P.W.G. Smith, A.R. Tatchell; Addison – Wesley Publishing Company, 2014.
  • Practical Organic Chemistry; Fourth Edition; F.C. Mann and B.C. Saunders; Pearson Education, New Delhi, 2013.
  • Advanced Practical Organic Chemistry; J. Leonard, B. Lygo and G. Procter; Third Edition; CRC Press, 2013
 
Academic Year: 
2020-2021
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